BARGE member profile — Dr Karen Bradham

Dr Karen Bradham

Methods Development and Application Branch (D205-05), National Exposure Research Laboratory, U.S. Environmental Protection Agency
Research Triangle Park
North Carolina
NC 27711



Diamond, G L, Bradham, K D, Brattin W J, Burgess, M, Griffin, S, Hawkins, C A, Juhasz, A L, Klotzbach, J M, Nelson, C, Lowney, Y W, Scheckel, K G, and Thomas, D J.  2016.  Predicting oral relative bioavailability of arsenic in soil from in vitro bioaccessibility.  Journal of Toxicology and Environmental Health, Part A, 79, 165–173.

Platten III, W E, Sylvest, N, Warren, C, Arambewela, M, Harmon, S, Bradham, K, Rogers, K, Thomas, T, and Luxton, T P.  2016.  Estimating dermal transfer of copper particles from the surfaces of pressure-treated lumber and implications for exposure.  Science of The Total Environment, 548–549, 441–449.

Starr, J M, Li, W, Graham, S E, Bradham, K D, Stout II, D M, Williams, A, and Sylva, J.  2016.  Using paired soil and house dust samples in an in vitro assay to assess the post ingestion bioaccessibility of sorbed fipronil.  Journal of Hazardous Materials, 312, 141–149.


Bradham, K D, Nelson, C, Juhasz, A L, Smith, E, Scheckel, K, Obenour, D R, Miller, B W, and Thomas, D J.  2015.  Independent Data Validation of an in Vitro Method for the Prediction of the Relative Bioavailability of Arsenic in Contaminated Soils.  Environmental Science & Technology, 49, 6312–6318

Santiago-Rodríguez, L, Griggs, J L, Bradham K D, Nelson, C, Luxton, T, Platten III, W E, and Rogers, K R.  2015.  Assessment of the bioaccessibility of micronized copper wood in synthetic stomach fluid.  Environmental Nanotechnology, Monitoring & Management, 4, 85–92.


Bradham, K D, Laird, B D, Rasmussen, P E, Schoof, R A, Serda, S M, Siciliano, S D, and Hughes, M F.  2014.  Assessing the bioavailability and risk from metal-contaminated soils and dusts.  Human and Ecological Risk Assessment: An International Journal, 20, 272–286

Juhasz, A L, Smith, E, Nelson, C, Thomas, D J, and Bradham, K.  2014.  Variability associated with As in vivo–in vitro correlations when using different bioaccessibility methodologies.  Environmental Science & Technology, 48, 11646–11653.


Bradham, K D, Diamond, G L, Scheckel, K G, Hughes, M F, Casteel, S W, Miller, B W, Klotzbach, J M, Thayer, W C, and Thomas, D J.  2013.  Mouse assay for determination of arsenic bioavailability in contaminated soils.  Journal of Toxicology and Environmental Health, Part A, 76, 815–826.

Mwilu, S K, El Badawy, A M, Bradham, K, Nelson, C, Thomas, D, Scheckel, K G, Tolaymat, T, Ma, L, and Roger, K R.  2013.  Changes in silver nanoparticles exposed to human synthetic stomach fluid: Effects of particle size and surface chemistry.  Environmental Science & Technology, 447, 90–98


Nelson, C M, Gilmore, T M, Harrington, J M, Scheckel, K G, Miller, B W, and Bradham, K D.  2012.  Evaluation of a low-cost commercially available extraction device for assessing lead bioaccessibility in contaminated soils.  Environmental Sciences: Processes and Impacts, 15, 573–578.


Bradham, K D, Scheckel, K G, Nelson, C M, Seales, P E, Lee, G E, Hughes, M F, Miller, B W, Yeow, A, Gilmore, T, Serda, S M, Harper, S, and Thomas, D J.  2011.   Relative bioavailability and bioaccessibility and speciation of arsenic in contaminated soils .  Environmental Health Perspectives, 119, 1629–1634


Medina-Vera, M, Van Emon, J M, Melnyk, L J, Bradham K D, Harper, S L, and Morgan, J N.  2010.  An overview of measurement method tools available to communities for conducting exposure and cumulative risk assessments.  Journal of Exposure Science and Environmental Epidemiology, 20, 359–370

Van de Wiele, T, Gallawa, C M, Kubachka, K M, Creed, J T, Basta, N, Dayton, E A, Whitacre, S, Du Laing, G, and Bradham, K.  2010.  Arsenic metabolism by human gut microbiota upon in vitro digestion of contaminated soils.  Environmental Health Perspective, 118, 1004–1009


Basta, N T, Scheckel, K G, Bradham, K D, Richey, J S, Dayton, E A, Whitacre, S W, and Casteel, S.  2008.  Soil chemical controls on arsenic bioaccessibility and bioavailability.  Epidemiology, 19


Bradham, K D, Dayton, E A, Basta, N T, Schroder, J, Payton, M, and Lanno, R P.  2006.  Effect of soil properties on lead bioavailability and toxicity to earthworms.  Environmental Toxicology and Chemistry, 25, 769–775


Brasfield, S M, Bradham, K, Wells, J B, Talent, L G, Lanno, R P, and Janz, D M.  2004.  Development of a terrestrial-vertebrate model for assessing bioavailability of cadmium in the fence lizard (Sceloporus undulatus) and in ovo effects on hatchling size and thyroid function.  Chemosphere, 54, 1643–1651

Lanno, R, Wells, J, Conder, J, Bradham, K, and Basta, N.  2004.  The bioavailability of chemicals in soil for earthworms.  Ecotoxicology and Environmental Safety, 57, 39–47